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中间体系列

阿奇沙坦
化学名称
2-乙氧基-1-[[2'-(4,5-二氢-5-氧代-1,2,4-恶二唑-3-基)联苯-4-基]甲基]苯并咪唑-7-羧酸
结构式
分子式
C25H20N4O5
分子量
456.49
CAS 号
147403-03-0
质量标准
Item Criteria Analysis Resultes
Appearance White or off-white powder Off-white powder
Identification-IR Conform to the reference spectrum Conform
Identification-HPLC Conform to the reference standard Conform
Loss on drying ≤0.5% 0.12%
Chloride ≤0.005% <0.005%
Residual solvents    
Methanol ≤3000ppm 200ppm
Dichloromethane ≤600ppm Not detected
Dimethyl sulfoxide ≤5000ppm Not detected
Related compounds    
Impurity A ≤0.3% 0.07%
Any individual impurity ≤0.1% 0.03%
Total impurities ≤0.5% 0.15%
Residue on ignition ≤0.1% 0.04%
Heavy metals ≤0.001% <0.001%
Assay ≥99.0% 99.7%
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